Discrete typing units of Trypanosoma cruzi identified in rural dogs and cats in the humid Argentinean Chaco
The discrete typing units (DTUs) of Trypanosoma cruzi that infect domestic dogs and cats have rarely been studied. With this purpose we conducted a cross-sectional xenodiagnostic survey of dog and cat populations residing in 2 infested rural villages in Pampa del Indio, in the humid Argentine Chaco....
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| Otros Autores: | , , , , |
| Formato: | Capítulo de libro |
| Lenguaje: | Inglés |
| Publicado: |
2013
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| Acceso en línea: | Registro en Scopus DOI Handle Registro en la Biblioteca Digital |
| Aporte de: | Registro referencial: Solicitar el recurso aquí |
| Sumario: | The discrete typing units (DTUs) of Trypanosoma cruzi that infect domestic dogs and cats have rarely been studied. With this purpose we conducted a cross-sectional xenodiagnostic survey of dog and cat populations residing in 2 infested rural villages in Pampa del Indio, in the humid Argentine Chaco. Parasites were isolated by culture from 44 dogs and 12 cats with a positive xenodiagnosis. DTUs were identified from parasite culture samples using a strategy based on multiple polymerase-chain reactions. TcVI was identified in 37 of 44 dogs and in 10 of 12 cats, whereas TcV was identified in 5 dogs and in 2 cats -a new finding for cats. No mixed infections were detected. The occurrence of 2 dogs infected with TcIII -classically found in armadillos- suggests a probable link with the local sylvatic transmission cycle involving Dasypus novemcinctus armadillos and a potential risk of human infection with TcIII. Our study reinforces the importance of dogs and cats as domestic reservoir hosts and sources of various DTUs infecting humans, and suggests a link between dogs and the sylvatic transmission cycle of TcIII. © Cambridge University Press 2012. |
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| Bibliografía: | Alvarado-Otegui, J.A., Ceballos, L.A., Orozco, M.M., Enriquez, G.F., Cardinal, M.V., Cura, C., Schijman, A.G., Gürtler, R.E., The sylvatic transmission cycle of Trypanosoma cruzi in a rural area in the humid Chaco of Argentina (2012) Acta Tropica, 124, pp. 79-86 Barnabé, C., Neubauer, K., Solari, A., Tibayrenc, M., Trypanosoma cruzi: Presence of the two major phylogenetic lineages and of several lesser discrete typing units (DTUs) in Chile and Paraguay (2001) Acta Tropica, 78, pp. 127-137 Barnabé, C., De Meeûs, T., Noireau, F., Bosseno, M.F., Monje, E.M., Renaud, F., Brenière, S.F., Trypanosoma cruzi discrete typing units (DTUs): Microsatellite loci and population genetics of DTUs TcV and TcI in Bolivia and Peru. Infection (2011) Genetics and Evolution, 11, pp. 1752-1760 Brisse, S., Verhoef, J., Tibayrenc, M., Characterization of large and small subunit rRNA and mini-exon genes further supports the distinction of six Trypanosoma cruzi lineages (2001) International Journal for Parasitology, 31, pp. 1218-1226 Burgos, J.M., Altcheh, J., Bisio, M., Duffy, T., Valdares, H.M.S., Seidenstein, M.E., Piccinali, R., Schijman, A.G., Direct molecular profiling of minicircle signatures and lineages of Trypanosoma cruzi bloodstream populations causing congenital Chagas disease (2007) International Journal for Parasitology, 37, pp. 1319-1327 Burgos, J.M., Diez, M., Vigliano, C., Bisio, M., Risso, M., Duffy, T., Cura, C., Schijman, A.G., Molecular identification of Trypanosoma cruzi discrete typing units in endstage chronic Chagas heart disease and reactivation after heart transplantation (2010) Clinical Infectious Disease, 51, pp. 485-495 Alvarado-Otegui, J.A., Ceballos, L.A., Orozco, M.M., Enriquez, G.F., Cardinal, M.V., Cura, C., Schijman, A.G., Gürtler, R.E., The sylvatic transmission cycle of Trypanosoma cruzi in a rural area in the humid Chaco of Argentina (2012) Acta Tropica, 124, pp. 79-86 Barnabé, C., Neubauer, K., Solari, A., Tibayrenc, M., Trypanosoma cruzi: Presence of the two major phylogenetic lineages and of several lesser discrete typing units (DTUs) in Chile and Paraguay (2001) Acta Tropica, 78, pp. 127-137 Barnabé, C., De Meeûs, T., Noireau, F., Bosseno, M.F., Monje, E.M., Renaud, F., Brenière, S.F., Trypanosoma cruzi discrete typing units (DTUs): Microsatellite loci and population genetics of DTUs TcV and TcI in Bolivia and Peru (2011) Infection Genetics and Evolution, 11, pp. 1752-1760 Brisse, S., Verhoef, J., Tibayrenc, M., Characterization of large and small subunit rRNA and mini-exon genes further supports the distinction of six Trypanosoma cruzi lineages (2001) International Journal for Parasitology, 31, pp. 1218-1226 Burgos, J.M., Altcheh, J., Bisio, M., Duffy, T., Valdares, H.M.S., Seidenstein, M.E., Piccinali, R., Schijman, A.G., Direct molecular profiling of minicircle signatures and lineages of trypanosoma cruzi bloodstream populations causing congenital chagas disease (2007) International Journal for Parasitology, 37, pp. 1319-1327 Burgos, J.M., Diez, M., Vigliano, C., Bisio, M., Risso, M., Duffy, T., Cura, C., Schijman, A.G., Molecular identification of Trypanosoma cruzi discrete typing units in endstage chronic Chagas heart disease and reactivation after heart transplantation (2010) Clinical Infectious Disease, 51, pp. 485-495 |
| ISSN: | 00311820 |
| DOI: | 10.1017/S003118201200159X |