Development and physicochemical evaluation of bilayered floating tablet of diltiazem hydrochloride prepared from Plantago ovata seed husk

The aim of the present study is to prepare bilayered floating tablets of diltiazem with different ratios of polymers like HPMC K4M, carbopol 934 P, sodium alginate, Plantago ovata seed husk (psyllium) and to carry out evaluation of the physicochemical parameters of tablets like hardness, friability,...

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Detalles Bibliográficos
Autores principales: Jana, Arun, Basu, Shyamoshree, Ali, Kazi A., Bandyopadhyay, Amal K.
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2010
Materias:
Farmacia
bilayered; diltiazem; floating; friability
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8052
http://www.latamjpharm.org/resumenes/29/7/LAJOP_29_7_2_1.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata
id I19-R120-10915-8052
record_format dspace
institution Universidad Nacional de La Plata
institution_str I-19
repository_str R-120
collection SEDICI (UNLP)
language Inglés
topic Farmacia
bilayered; diltiazem; floating; friability
spellingShingle Farmacia
bilayered; diltiazem; floating; friability
Jana, Arun
Basu, Shyamoshree
Ali, Kazi A.
Bandyopadhyay, Amal K.
Development and physicochemical evaluation of bilayered floating tablet of diltiazem hydrochloride prepared from Plantago ovata seed husk
topic_facet Farmacia
bilayered; diltiazem; floating; friability
description The aim of the present study is to prepare bilayered floating tablets of diltiazem with different ratios of polymers like HPMC K4M, carbopol 934 P, sodium alginate, Plantago ovata seed husk (psyllium) and to carry out evaluation of the physicochemical parameters of tablets like hardness, friability, content uniformity, weight variation, in vitro buoyancy and in vitro dissolution profiles. In vivo X-ray study was done in human volunteers to determine the floating characteristics of the placebo tablets for a period of 12 h.
format Articulo
Comunicacion
author Jana, Arun
Basu, Shyamoshree
Ali, Kazi A.
Bandyopadhyay, Amal K.
author_facet Jana, Arun
Basu, Shyamoshree
Ali, Kazi A.
Bandyopadhyay, Amal K.
author_sort Jana, Arun
title Development and physicochemical evaluation of bilayered floating tablet of diltiazem hydrochloride prepared from Plantago ovata seed husk
title_short Development and physicochemical evaluation of bilayered floating tablet of diltiazem hydrochloride prepared from Plantago ovata seed husk
title_full Development and physicochemical evaluation of bilayered floating tablet of diltiazem hydrochloride prepared from Plantago ovata seed husk
title_fullStr Development and physicochemical evaluation of bilayered floating tablet of diltiazem hydrochloride prepared from Plantago ovata seed husk
title_full_unstemmed Development and physicochemical evaluation of bilayered floating tablet of diltiazem hydrochloride prepared from Plantago ovata seed husk
title_sort development and physicochemical evaluation of bilayered floating tablet of diltiazem hydrochloride prepared from plantago ovata seed husk
publishDate 2010
url http://sedici.unlp.edu.ar/handle/10915/8052
http://www.latamjpharm.org/resumenes/29/7/LAJOP_29_7_2_1.pdf
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AT alikazia developmentandphysicochemicalevaluationofbilayeredfloatingtabletofdiltiazemhydrochloridepreparedfromplantagoovataseedhusk
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