Amyloidogenic propensity of a natural variant of human apolipoprotein A-I: Stability and interaction with ligands

A number of naturally occurring mutations of human apolipoprotein A-I (apoA-I) have been associated with hereditary amyloidoses. The molecular mechanisms involved in amyloid-associated pathology remain largely unknown. Here we examined the effects of the Arg173Pro point mutation in apoA-I on the str...

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Detalles Bibliográficos
Autores principales: Rosu, Silvana Antonia, Rimoldi, Omar Jorge, Prieto, Eduardo Daniel, Curto, Lucrecia M., Delfino, José M., Ramella, Nahuel Alberto, Tricerri, María Alejandra
Formato: Articulo
Lenguaje:Inglés
Publicado: 2015
Materias:
Ciencias Médicas
Apolipoprotein A-I
Lipoproteins
HDL particles
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/86136
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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