Amine-induced deacylation of carbohydrate derivatives under anhydrous conditionsw*
Methanolysis of acylated carbohydrate derivatives was effectively performed using tertiary amines in the absence of water at room temperature. The reaction was performed with acetylated and benzoylated alditols, aldoses, lactones, orthoesters, glycosides, and disaccharides. ^-methyl-pyrrolidine prov...
| Autores principales: | , |
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| Publicado: |
1993
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07328303_v12_n1_p13_Moradei http://hdl.handle.net/20.500.12110/paper_07328303_v12_n1_p13_Moradei |
| Aporte de: |
| Sumario: | Methanolysis of acylated carbohydrate derivatives was effectively performed using tertiary amines in the absence of water at room temperature. The reaction was performed with acetylated and benzoylated alditols, aldoses, lactones, orthoesters, glycosides, and disaccharides. ^-methyl-pyrrolidine proved to be especially suitable for synthetic purposes and deacylated compounds were obtained in excellent yields. The mild conditions employed and the minimum work-up needed make this method appropriate for the deacylation of labile compounds. © 1993, Taylor & Francis Group, LLC. All rights reserved. |
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