Carbohydrate PEGylation, an approach to improve pharmacological potency

Conjugation with polyethylene glycol (PEG), known as PEGylation, has been widely used to improve the bioavailability of proteins and low molecular weight drugs. The covalent conjugation of PEG to the carbohydrate moiety of a protein has been mainly used to enhance the pharmacokinetic properties of t...

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Detalles Bibliográficos
Autores principales:	Giorgi, María Eugenia, Agustí, Rosalía, Muchnik de Lederkremer, Rosa María
Publicado:	2014
Materias:	Bioavailability Carbohydrates Conjugates Glycopegylation Multivalent glycosystems Multivalent PEGylation
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_18605397_v10_n_p1433_Giorgi http://hdl.handle.net/20.500.12110/paper_18605397_v10_n_p1433_Giorgi
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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