Effect of transdermal teriparatide administration on bone mineral density in postmenopausal women

Context: Treatment of osteoporosis with an anabolic agent, teriparatide [human PTH 1-34 (TPTD)], is effective in reducing incident fractures, but patient resistance to daily sc injections has limited its use. A novel transdermal patch, providing a rapid, pulse delivery of TPTD, may provide a desirab...

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Detalles Bibliográficos
Autores principales: Cosman, F., Lane, N.E., Bolognese, M.A., Zanchetta, J.R., Garcia-Hernandez, P.A., Sees, K., Matriano, J.A., Gaumer, K., Daddona, P.E.
Formato: JOUR
Materias:
carboxy terminal telopeptide
parathyroid hormone[1-34]
placebo
procollagen
procollagen type i n terminal propeptide
unclassified drug
adult
aged
area under the curve
arthralgia
article
bleeding
bone density
bone turnover
calcium blood level
clinical trial
controlled clinical trial
controlled study
creatinine urine level
dizziness
dose response
drug absorption
drug dose comparison
drug efficacy
drug hypersensitivity
drug safety
drug tolerability
drug withdrawal
edema
erythema
female
human
hypercalcemia
hypercalciuria
hyperpigmentation
hypotension
injection site erythema
lumbar spine
major clinical study
maximum plasma concentration
multicenter study
nausea
nephrolithiasis
osteoporosis
pain
postmenopause
priority journal
randomized controlled trial
side effect
skin infection
syncope
tachycardia
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0021972X_v95_n1_p151_Cosman
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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