Regulation of Tacaribe mammarenavirus translation: Positive 5' and negative 3' elements and role of key cellular factors

Mammarenaviruses are enveloped viruses with a bisegmented negativestranded RNA genome that encodes the nucleocapsid protein (NP), the envelope glycoprotein precursor (GPC), the RNA polymerase (L), and a RING matrix protein (Z). Viral proteins are synthesized from subgenomic mRNAs bearing a capped 5&...

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Detalles Bibliográficos
Autores principales: Foscaldi, S., D'Antuono, A., Noval, M.G., Gay, G.P., Scolaro, L., Lopez, N.
Formato: JOUR
Materias:
Arenavirus
MRNA
Translation
initiation factor 4E
initiation factor 4G
messenger RNA
nucleocapsid protein
viral protein
3' untranslated region
5' untranslated region
regulatory RNA sequence
Article
carboxy terminal sequence
controlled study
down regulation
gene sequence
gene structure
genetic transcription
nonhuman
priority journal
protein blood level
protein expression
reporter gene
RNA interference
RNA sequence
RNA translation
Tacaribe virus
translation regulation
virus gene
animal
cell line
gene expression regulation
genetics
host pathogen interaction
human
metabolism
New World arenavirus
protein synthesis
3' Untranslated Regions
5' Untranslated Regions
Animals
Arenaviruses, New World
Cell Line
Eukaryotic Initiation Factor-4E
Eukaryotic Initiation Factor-4G
Gene Expression Regulation, Viral
Host-Pathogen Interactions
Humans
Protein Biosynthesis
Regulatory Sequences, Ribonucleic Acid
RNA, Messenger
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0022538X_v91_n14_p_Foscaldi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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