Calcineurin phosphatase as a negative regulator of fear memory in hippocampus: Control on nuclear factor-κB signaling in consolidation and reconsolidation

Protein phosphatases are important regulators of neural plasticity and memory. Some studies support that the Ca2+/calmodulin-dependent phosphatase calcineurin (CaN) is, on the one hand, a negative regulator of memory formation and, on the other hand, a positive regulator of memory extinction and rev...

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Detalles Bibliográficos
Autores principales: de la Fuente, V., Federman, N., Fustiñana, M.S., Zalcman, G., Romano, A.
Formato: JOUR
Materias:
Calcineurin
Consolidation
Fear conditioning
Hippocampus
NF-κB
Reconsolidation
calcineurin
immunoglobulin enhancer binding protein
salazosulfapyridine
tacrolimus
calcineurin inhibitor
calcineurin phosphatase
central nervous system agents
phosphatase
animal experiment
animal tissue
Article
controlled study
dorsal hippocampus
facilitation
fear conditioning test
hippocampus
male
memory consolidation
mouse
nonhuman
recall
reinforcement
signal transduction
animal
antagonists and inhibitors
C57BL mouse
conditioned reflex
drug effects
electric shock
fear
memory
metabolism
neuropsychological test
physiology
Animals
Calcineurin Inhibitors
Central Nervous System Agents
Conditioning, Classical
Electroshock
Fear
Male
Memory
Mice, Inbred C57BL
Neuropsychological Tests
NF-kappa B
Phosphoric Monoester Hydrolases
Signal Transduction
Sulfasalazine
Tacrolimus
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_10509631_v24_n12_p1549_delaFuente
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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