Segmentation of the zebrafish axial skeleton relies on notochord sheath cells and not on the segmentation clock

Segmentation of the axial skeleton in amniotes depends on the segmentation clock, which patterns the paraxial mesoderm and the sclerotome. While the segmentation clock clearly operates in teleosts, the role of the sclerotome in establishing the axial skeleton is unclear. We severely disrupt zebrafis...

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Detalles Bibliográficos
Autores principales: Lleras Forero, L., Narayanan, R., Huitema, L.F.A., Vanbergen, M., Apschner, A., Peterson-Maduro, J., Logister, I., Valentin, G., Morelli, L.G., Oates, A.C., Schulte-Merker, S.
Formato: JOUR
Materias:
amniote
Article
axial patterning
coccygeal vertebra
controlled study
DNA binding
embryo
embryo segmentation
gene expression
in situ hybridization
mesoderm
muscle cell
myotome
nonhuman
notochord
ossification
osteoblast
promoter region
sclerotome
stop codon
teleost
vertebra body
zebra fish
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_2050084X_v7_n_p_LlerasForero
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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