Activation of the p53 tumor suppressor and its multiple roles in cell cycle and apoptosis

p53 is a widely conserved tumor suppressor protein that is frequently inactivated in human cancer. p53 functions primarily as a transcription factor regulating the expression of a growing repertoire of target genes. p53 integrates signals from many stress-activated pathways and is subject to multipl...

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Detalles Bibliográficos
Autores principales:	Giono, L.E., Manfredi, J.J.
Formato:	CHAP
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_97836420_v_n_p375_Giono
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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