Activation of the p53 tumor suppressor and its multiple roles in cell cycle and apoptosis
p53 is a widely conserved tumor suppressor protein that is frequently inactivated in human cancer. p53 functions primarily as a transcription factor regulating the expression of a growing repertoire of target genes. p53 integrates signals from many stress-activated pathways and is subject to multipl...
Autores principales: | Giono, L.E., Manfredi, J.J. |
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Formato: | CHAP |
Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_97836420_v_n_p375_Giono |
Aporte de: |
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