cruzipain Trypanosoma cruzi 46 nonhuman 42 article 38 Cysteine Endopeptidases 36 priority journal 36 cysteine proteinase 32 Animals 26 controlled study 24 Cruzipain 22 Humans 20 unclassified drug 18 carboxy terminal sequence 16 mouse 16 Chagas disease 15 Chagas Disease 14 Mice 14 animal 14 enzyme activity 14 human 14 Animal 12 Support, Non-U.S. Gov't 12 animal experiment 12 epimastigote 12 metabolism 12 sulfate 12 trypanosoma cruzi 12 Immunoglobulin G 10 Mice, Inbred BALB C 10 Rabbits 10