Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents

Synthesis and biological evaluation of a novel library of fused 1,2,3-triazole derivatives are described. The in-house developed multicomponent reaction based on commercially available starting materials was applied and broad biological screening against various viruses was performed, showing promis...

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Autores principales: Karypidou, Konstantina, Ribone, Sergio Roman, Quevedo, Mario Alfredo, Persoons, Leentje, Pannecouque, Christophe, Helsen, Christine, Claessens, Frank, Dehaen, Wim
Formato: article
Lenguaje:Español
Publicado: 2021
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Acceso en línea:https://doi.org/10.1016/j.bmcl.2018.09.019
http://hdl.handle.net/11086/19824
https://www.sciencedirect.com/science/article/abs/pii/S0960894X18307509?via%3Dihub
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