Effectiveness and safety of COVID-19 vaccines in healthcare workers in Buenos Aires City, Argentina.

COVID-19 vaccination aids pandemic limitation. In Argentina, three vaccines are approved, and healthcare workers are priorized (HCWs). The aim was to determine the effectiveness of COVID-19 vaccines, analyzing change in Immunoglobulin G levels and the incidence of new COVID-19 cases up to 12 months...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Pagotto, Vanina, Seoane, Facundo, Arrigo, Diego, Ardiles, Victoria, Asprea, Valeria, De Florio, Florencia, Ferloni, Analia, Aliperti, Valeria
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional Córdoba. Facultad de Ciencias Médicas. Secretaria de Ciencia y Tecnología 2024
Materias:
Acceso en línea:https://revistas.unc.edu.ar/index.php/med/article/view/41155
Aporte de:
Descripción
Sumario:COVID-19 vaccination aids pandemic limitation. In Argentina, three vaccines are approved, and healthcare workers are priorized (HCWs). The aim was to determine the effectiveness of COVID-19 vaccines, analyzing change in Immunoglobulin G levels and the incidence of new COVID-19 cases up to 12 months after the second dose. Methods: Prospective cohort of HCWs between March 2021- 2022.  COVIDAR IgG test was used to measure antibodies. A mixed-effects model was employed to compare the levels of immunoglobulin G at different time points, Kaplan Meier was used to estimate incident COVID-19 cases. Results: 82 participants were included Adverse events were frequent but mild.  All participant showed positive antibody at 12 months. Antibodies levels showed an increase one year after 2nd dose. Sinopharm took a long time to yield positive results.  More than half of the people had mild COVID-19 disease. Conclusion COVID-19 vaccines are safe and effective.