Dyslipidemia in patients with HIV

Abstract Since the introduction of highly active antiretroviral therapy (ART) in the treatment of HIV/AIDS patients, we have observed a change in the development of the disease, becoming a chronic therapeutically containable condition. The increase in survival goes together with associated...

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Autores principales: Puppo, D., Torales M., J., Duarte, S., Pandolfi, M.
Formato: Artículo revista
Lenguaje:Español
Publicado: Escuela de Salud Pública y Ambiente. Fac. Cs. Médicas UNC 2015
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Acceso en línea:https://revistas.unc.edu.ar/index.php/RSD/article/view/11733
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Sumario:Abstract Since the introduction of highly active antiretroviral therapy (ART) in the treatment of HIV/AIDS patients, we have observed a change in the development of the disease, becoming a chronic therapeutically containable condition. The increase in survival goes together with associated diseases; cardiovascular ones have become relevant, being earlier and more severe. Dyslipidemias have a leading role in this pathology. In this work, we analyze their incidence and characteristics in HIV patients, with and without ART treatment. Lipid profile was different in the pre-treatment stage (low HDL, low total Cholesterol and normal TG) from the stage under ART (marked increase of TG and to a lesser extent of total Cholesterol and LDL), with a significant association of the use of Protease Inhibitors (PIs) and CD4 levels lower than 200/mm3.