Determination of the main solid-state form of albendazole in bulk drug, employing Raman spectroscopy coupled to multivariate analysis

Albendazole (ALB) is a broad-spectrum anthelmintic, which exhibits two solid-state forms (Forms I and II). The Form I is the metastable crystal at room temperature, while Form II is the stable one. Because the drug has poor aqueous solubility and Form II is less soluble than Form I, it is desirabl...

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Detalles Bibliográficos
Autores principales: Calvo, Natalia Lorena, Arias, Juan Marcelo, Ben Altabef, Aída, Maggio, Rubén Mariano, Kaufman, Teodoro Saúl
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Elsevier 2020
Materias:
Albendazole
Chemometrics
PLS
Raman Spectroscopy
Solid State Forms
Acceso en línea:http://hdl.handle.net/2133/17590
http://hdl.handle.net/2133/17590
Aporte de:
Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

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