Structural and mutational analyses of the Leptospira interrogans virulence-related heme oxygenase provide insights into its catalytic mechanism

Heme oxygenase from Leptospira interrogans is an important virulence factor. During catalysis, redox equivalents are provided to this enzyme by the plastidic-type ferredoxin-NADP+ reductase also found in L. interrogans. This process may have evolved to aid this bacterial pathogen to obtain heme-ir...

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Autores principales: Soldano, Anabel, Klinke, Sebastián, Otero, Lisandro H., Rivera, Mario, Catalano-Dupuy, Daniela L., Ceccarelli, Eduardo Augusto
Formato: article artículo publishedVersion
Lenguaje:Inglés
Publicado: Public Library of Science (PLOS) 2021
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Acceso en línea:http://hdl.handle.net/2133/19676
http://hdl.handle.net/2133/19676
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