CuA-based chimeric T1 copper sites allow for independent modulation of reorganization energy and reduction potential

Attaining rational modulation of thermodynamic and kinetic redox parameters of metalloproteins is a key milestone towards the (re)design of proteins with new or improved redox functions. Here we report that implantation of ligand loops from natural T1 proteins into the scaffold of a CuA protein le...

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Detalles Bibliográficos
Autores principales:	Szuster, Jonathan, Zitare, Ulises A., Castro, María A., Leguto, Alcides J., Morgada, Marcos Nicolás, Vila, Alejandro J., Murgida, Daniel H.
Formato:	article artículo publishedVersion
Lenguaje:	Inglés
Publicado:	Royal Society of Chemistry 2021
Materias:	Copper Metalloproteins Oxidation-Reduction Ligands
Acceso en línea:	http://hdl.handle.net/2133/20481 http://hdl.handle.net/2133/20481
Aporte de:	Repositorio Hipermedial de la Universidad Nacional de Rosario (UNR) de Universidad Nacional de Rosario

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