Deciphering the evolution of metallo-β-lactamases: A journey from the test tube to the bacterial periplasm
Understanding the evolution of metallo-β-lactamases (MBLs) is fundamental to deciphering the mechanistic basis of resistance to carbapenems in pathogenic and opportunistic bacteria. Presently, these MBL-producing pathogens are linked to high rates of morbidity and mortality worldwide. However, the s...
Guardado en:
| Autores principales: | López, Carolina, Delmonti, Juliana, Bonomo, Robert A., Vila, Alejandro J. |
|---|---|
| Formato: | article artículo publishedVersion |
| Lenguaje: | Inglés |
| Publicado: |
American Society for Biochemistry and Molecular Biology Inc.
2022
|
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/2133/23340 http://hdl.handle.net/2133/23340 |
| Aporte de: |
Ejemplares similares
-
Metallo-β-lactamases and a tug-of-war for the available zinc at the host–pathogen interface
por: Bahr, Guillermo, et al.
Publicado: (2022) -
Protein determinants of dissemination and host specificity of metallo-β-lactamases
por: López, Carolina, et al.
Publicado: (2021) -
A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases
por: Lisa, María Natalia, et al.
Publicado: (2021) -
Metallo-β-lactamase inhibitors inspired on snapshots from the catalytic mechanism
por: Palacios, Antonela R., et al.
Publicado: (2021) -
Pseudomonas putida group species as reservoirs of mobilizable Tn402-like class 1 integrons carrying blaVIM-2 metallo-β-lactamase genes
por: Brovedan, Marco Alcides, et al.
Publicado: (2022)