Integrated Application of Enhanced Replacement Method and Ensemble Learning for the Prediction of BCRP/ABCG2 Substrates
Breast Cancer Resistance Protein (BCRP or ABCG2) is a polyspecific efflux-transporter which belongs to the ATP-binding Cassette superfamily. Up-regulation of BCRP is associated to multi-drug resistance in a number of conditions, e.g. cancer and epilepsy. Recent proteomic studies show that high-expre...
Guardado en:
| Autores principales: | Gantner, Melisa Edith, Alberca, Lucas Nicolás, Mercader, Andrew Gustavo, Bruno Blanch, Luis Enrique, Talevi, Alan |
|---|---|
| Formato: | Articulo Preprint |
| Lenguaje: | Inglés |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | http://sedici.unlp.edu.ar/handle/10915/118321 |
| Aporte de: |
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