Baculovirus-based gene silencing of Humanin for the treatment of pituitary tumors

Pituitary tumors are the most common primary intracranial neoplasms. Humanin (HN) and Rattin (HNr), a rat homolog of HN, are short peptides with a cytoprotective action. In the present study, we aimed to evaluate whether endogenous HNr plays an antiapoptotic role in pituitary tumor cells. Thus, we u...

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Detalles Bibliográficos
Autores principales: Gottardo, María Florencia, Pidre, Matías Luis, Zuccato, Camila Florencia, Asad, Antonela Sofía, Imsen, Mercedes, Jaita, Gabriela, Candolfi, Marianela, Romanowski, Víctor, Seilicovich, Adriana
Formato: Articulo
Lenguaje:Inglés
Publicado: 2018
Materias:
Biología
Medicina
Humanin
Rattin
Baculovirus
ShRNA
Pituitary tumor
Apoptosis
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/139708
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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