Development and Validation of LC-MS/MS Method for Determination of Ondansetron in rat Plasma and its Application

A selective and sensitive liquid chromatography-mass spectrometry (LC–MS) method for determination of ondansetron in rat plasma was developed and validated. After addition of midazolam as internal standard (IS), protein precipitation by acetonitrile was used as sample preparation, and chromatography...

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Detalles Bibliográficos
Autores principales: Pang, Lingxia, Wang, Qing, Wang, Youpei, Zheng, Meiqin, Wu, Haiya, Wang, Zhiyi
Formato: Articulo Comunicacion
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Farmacología
LC-MS; ondansetron; pharmacokinetics; rat plasma
Farmacocinética
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/18129
http://www.latamjpharm.org/resumenes/31/2/LAJOP_31_2_2_1.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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