Fosinopril improves liver fibrosis by upregulating ACE2/Angiotensin-(1-7) axis activation in rats with nonalcoholic steatohepatitis

The aim of this research was to evaluate the effect of the angiotensin converting enzyme (ACE) inhibitor fosinopril on liver fibrosis in rats with high fat diet (HFD) induced nonalcoholic steatohepatitis (NASH). We found that treatment with fosinopril improved liver fibrosis. Moreover, treatment wit...

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Detalles Bibliográficos
Autores principales: Liu, Bo, Wu, Rong, Zhang, Wei, Zhang, Feng, Zhou, Huamei, Wang, Lulu, Xiao, Xiaoqiu, Zhang, Xia, Wu, Xiaoling
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Adiponectin
Angiotensin converting enzyme 2
Fosinopril
Leptin
Liver fibrosis
Non-alcoholic steatohepatitis
Fibrosis
Ratas
Leptina
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/20188
http://www.latamjpharm.org/resumenes/31/4/LAJOP_31_4_1_15.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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