Use of response surface methodology to optimize chitosan microparticles for sustained release of curcumin

Chitosan microparticles (Cs-MPs) for the dissolution and oral bioavailability improvement of curcumin (Cur) were prepared with sodium tripolyphosphate (TPP) by ionotropic gelation method. Response surface methodology (RSM) based on a three-factor, three-level Box-Behnken Design (BBD), was used to op...

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Detalles Bibliográficos
Autores principales: Sun, Yingqian, Wan, Shuxin, Zhou, Lijun
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Metodología
Curcumina
Chitosan microparticles
Curcumin
Oral bioavailability
Response surface methodology
Sustained release
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/20190
http://www.latamjpharm.org/resumenes/31/4/LAJOP_31_4_1_17.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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