Feline immunodeficiency virus infection: A comparative study of different diagnostic techniques

This study evaluated an indirect immunofluorescence assay (IFA) to detect feline immunodeficiency virus infection (FIV) antibody in a comprehensive epidemiological survey of FIV in Argentina. IFA modified in our laboratory, was compared with two other immunoassays, western blot (WB) and a sandwich i...

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Autores principales: Mórtola, Eduardo Carlos, Oliva, Graciela A., Risso, Miguel Atilio, Pecoraro, Marcelo Ricardo Ítalo, Venturini, María Cecilia
Formato: Articulo
Lenguaje:Inglés
Publicado: 2004
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/29731
http://www.scielo.br/pdf/abmvz/v56n1/a03v56n1.pdf
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Sumario:This study evaluated an indirect immunofluorescence assay (IFA) to detect feline immunodeficiency virus infection (FIV) antibody in a comprehensive epidemiological survey of FIV in Argentina. IFA modified in our laboratory, was compared with two other immunoassays, western blot (WB) and a sandwich immunochromatographic commercial kit (SI), and also with a direct polymerase chain reaction (PCR) method that detects proviral DNA. IFA showed to be a test with high sensitivity and specificity, and could be useful as a diagnostic tool in epidemiological studies. The presence of a low percentage of results with non-specific reactivity in the IFA could be resolved with further testing or use of an alternative method.