Chronomodulated rupturable pulsatile drug delivery of theophylline: preparation and in vitro characterization

The aim of the present study was to develop and evaluate chronomodulated rupturable pulsatile drug delivery of theophylline for the treatment of nocturnal asthma. Core tablets containing theophylline were coated with two consecutive layers, an inner swelling layer and an outer rupturable coating...

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Autores principales: Mahajan, Ashok N., Pancholi, Shyam S.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2010
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8065
http://www.latamjpharm.org/resumenes/29/8/LAJOP_29_8_1_5.pdf
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