In vitro and In vivo toxicology evaluation to determine suitable biomedical Polymers for development of a papain-containing drug delivery system

Papain has been known by many decades for wounded tissues repair. However, papain stability is not high enough to be commercialized in a stable pharmaceutical form; therefore its use is limited. The strategy to entrap papain into a polymeric matrix to provide an adequate drug delivery system consist...

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Detalles Bibliográficos
Autores principales: Alcântara, Mara T. S., Velasco, María Valéria R., Zulli, Gislaine, Lopes, Patrícia S., Miyamaru, Lígia L., Bárbara, Maria C.S., Rogero, Suize O., Lugão, Ademar B., Mathor, Monica B.
Formato: Articulo
Lenguaje:Inglés
Publicado: 2011
Materias:
Farmacia
cutaneous irritation test; cytotoxicity test; drug delivery system; papain
Enzimas
Pruebas de Toxicidad
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8268
http://www.latamjpharm.org/resumenes/30/6/LAJOP_30_6_1_10.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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