Evaluation of a blocking ELISA using a urease conjugate for the detection of antibodies to pseudorabies virus

A blocking enzyme-linked immunosorbent assay (ELISA) using a urease conjugate (U-B-ELISA) was evaluated for screening sera for antibodies to pseudorabies virus under field conditions, A total of 764 serum samples were analyzed by U-B-ELISA. Of these, 264 were evaluated by both virus neutralization a...

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Autores principales: Echeverría, María Gabriela, Nosetto, Edgardo Omar, Etcheverrigaray, María Elisa
Formato: Articulo
Lenguaje:Inglés
Publicado: 2000
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/83521
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Sumario:A blocking enzyme-linked immunosorbent assay (ELISA) using a urease conjugate (U-B-ELISA) was evaluated for screening sera for antibodies to pseudorabies virus under field conditions, A total of 764 serum samples were analyzed by U-B-ELISA. Of these, 264 were evaluated by both virus neutralization and U-B-ELISA, and the results were compared. U-B-ELISA showed 98.5% and 98.9% sensitivity and specificity, respectively. This test combines the sensitivity and specificity of the blocking ELISA format while allowing visual assessment of results.