Development and characterization of biodegradable chitosan nanoparticles loaded with lovastatin using factorial design

The objective of the present work was to formulate chitosan nanoparticles as carriers for the lovastatin, since this drug undergoes extensive first pass extraction in the liver, and bioavailibity is low (< 5 %). Nanoparticles were prepared by modified ionotropic gelation method using 32 full fact...

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Detalles Bibliográficos
Autores principales: More, Harinath N., Shinde, Anilkumar J.
Formato: Articulo
Lenguaje:Español
Publicado: 2011
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8380
http://www.latamjpharm.org/resumenes/30/9/LAJOP_30_9_1_24.pdf
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