Development and validation of LC-ESI-MS method for the quantification of dapoxetine in rat plasma

A sensitive and simple liquid chromatography/electrospray mass spectrometry (LC-ESI-MS) method for determination of dapoxetine in rat plasma using one-step protein precipitation was developed and validated. After addition of midazolam as internal standard (IS), protein precipitation by acetonitrile...

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Detalles Bibliográficos
Autores principales: Ma, Jianshe, Luo, Shunbin, Chen, Chan, Wang, Jinjin, Wang, Zhibin, Wang, Zhiyi
Formato: Articulo
Lenguaje:Inglés
Publicado: 2012
Materias:
Farmacia
Serotonina
Espectrometría de Masas
Cromatografía Liquida
Plasma
Ratas
Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/8421
http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_1_1.pdf
Aporte de:
SEDICI (UNLP) de Universidad Nacional de La Plata

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