Docking applied to the prediction of the affinity of compounds to p-glycoprotein

P-glycoprotein (P-gp) is involved in the transport of xenobiotic compounds and responsible for the decrease of the drug accumulation in multi-drug-resistant cells. In this investigation we compare several docking algorithms in order to find the conditions that are able to discriminate between P-gp b...

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Detalles Bibliográficos
Autores principales:	Palestro, Pablo Hernán, Gavernet, Luciana, Estiú, Guillermina, Bruno Blanch, Luis Enrique
Formato:	Articulo
Lenguaje:	Inglés
Publicado:	2014
Materias:	Química P-Glycoprotein ATP-Binding Cassette Transporters Nucleotide binding
Acceso en línea:	http://sedici.unlp.edu.ar/handle/10915/85173
Aporte de:	SEDICI (UNLP) de Universidad Nacional de La Plata

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