Aging and CaMKII alter intracellular Ca2+ transients and heart rhythm in Drosophila melanogaster

Aging is associated to disrupted contractility and rhythmicity, among other cardiovascular alterations. Drosophila melanogaster shows a pattern of aging similar to human beings and recapitulates the arrhythmogenic conditions found in the human heart. Moreover, the kinase CaMKII has been characterize...

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Autores principales: Santalla, Manuela, Valverde, Carlos Alfredo, Harnichar, E., Lacunza, Ezequiel, Aguilar Fuentes, J., Mattiazzi, Alicia Ramona, Ferrero, Paola Viviana
Formato: Articulo
Lenguaje:Inglés
Publicado: 2014
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Acceso en línea:http://sedici.unlp.edu.ar/handle/10915/85638
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