Inventario de antimicrobianos empleados en la ganadería bovina en Argentina: Establecimiento de Dosis Diarias Definidas y Dosis de Curso Definidas para la cuantificación del uso

Standardizing the units used for the animals’ treatments with antimicrobials is crucial to enable clear quantification and to compare with other species and regions. The aim of this study was to assign the Defined Daily Doses (DDDvetArg) and Defined Course Doses (DCDvetArg) for cattle in Argentina,...

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Detalles Bibliográficos
Autores principales: Peña, Agostina, Miotti, Camila, Cicotello, Joaquin, Welschen, Nicolas, Tello D'Elia, Facundo, Suarez Archilla, Guillermo, Astesana, Diego, Zbrun, María Virginia, Signorini, Marcelo, Camussone, Camila, Molineri, Ana Inés
Formato: Artículo revista
Lenguaje:Español
Publicado: Universidad Nacional del Litoral 2026
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Acceso en línea:https://bibliotecavirtual.unl.edu.ar/publicaciones/index.php/index/article/view/15484
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Sumario:Standardizing the units used for the animals’ treatments with antimicrobials is crucial to enable clear quantification and to compare with other species and regions. The aim of this study was to assign the Defined Daily Doses (DDDvetArg) and Defined Course Doses (DCDvetArg) for cattle in Argentina, for each antimicrobial and route of administration, using the information obtained from the product label and veterinary vademecums. Fifty-seven laboratories were identified, and the products were classified according to the route of administration (oral, intrauterine and topic). A total of 28 formulations for oral administration were recorded, and 30 corresponding to intrauterine and topical routes of administration. In case it was necessary, standard weights were applied for the doses calculation. From this information, a database was generated to calculate the DDDvetAr and DCDvetArg.  The products that contained antimicrobials as growth promotors were excluded, as they are forbidden in Argentina since 2019. The doses standardization allows more precise surveillance about the antimicrobial use in cattle, which is key facing the global challenge of antimicrobial resistance.