The metabolic adaptation evoked by arginine enhances the effect ofradiation in brain metastases

Abstract: Selected patients with brain metastases (BM) are candidates for radiotherapy. A lactatogenic metabolism, common in BM, has been associated with radioresistance. We demonstrated that BM express nitric oxide (NO) synthase 2 and that administration of its substrate L-arginine decreases tumor...

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Detalles Bibliográficos
Autores principales: Marullo, Rossella, Castro, Mónica, Yomtoubian, Shira, Calvo Vidal, M. Nieves, Revuelta, María Victoria, Krumsiek, Jan, Cho, Andrew, Cresta Morgado, Pablo, Yang, ShaoNing, Medina, Vanina Araceli, Roth, Berta M., Bonomi, Marcelo, Keshari, Kayvan R., Mittal, Vivek, Navigante, Alfredo, Cerchietti, Leandro
Formato: Artículo
Lenguaje:Inglés
Publicado: American Association for the Advancement of Science 2022
Materias:
METASTASIS
CEREBRO
TUMORES
ARGININA
RADIACION
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/14019
Aporte de:
Repositorio Institucional de la Universidad Católica Argentina (UCA) de Universidad Católica Argentina

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