TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis
Abstract: Structural cardiac remodeling, accompanying cytoskeletal reorganization of cardiac cells, is a major clinical outcome of diastolic heart failure. A highly local Ca2+ influx across the plasma membrane has been suggested to code signals to induce Rho GTPase-mediated fibrosis, but it is obscu...
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| Autores principales: | Numaga-Tomita, Takuro, Kitajima, Naoyuki, Kuroda, Takuya, Nishimura, Akiyuki, Miyano, Kei, Yasuda, Satoshi, Kuwahara, Koichiro, Sato, Yoji, Ide, Tomomi, Birnbaumer, Lutz, Sumimoto, Hideki, Mori, Yasuo, Nishida, Motohiro |
|---|---|
| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
Nature Research
2019
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| Materias: | |
| Acceso en línea: | https://repositorio.uca.edu.ar/handle/123456789/8746 |
| Aporte de: |
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