Diurnal ACTH and plasma cortisol variations in healthy dogs and in those with pituitary-dependent Cushing's syndrome before and after treatment with retinoic acid

Daytime variations in ACTH and plasma cortisol were studied in healthy dogs and in dogs with pituitary-dependent hypercortisolism (PDH), before and after treatment with retinoic acid. In control dogs ACTH showed a higher concentration at 8.00 AM and between 2.00 and 6.00 PM, with the lowest concentr...

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Autores principales: Castillo, V.A., Cabrera Blatter, M.F., Gómez, N.V., Sinatra, V., Gallelli, M.F., Ghersevich, María Carolina
Formato: Artículo
Lenguaje:Español
Publicado: 2009
Materias:
SF Cultura de los animales
Acceso en línea:http://pa.bibdigital.ucc.edu.ar/4944/1/A_Castillo.pdf
Aporte de:
Producción Académica Universidad Católica de Córdoba (UCCor) de Universidad Católica de Córdoba
id I38-R144-4944
record_format dspace
spelling I38-R144-49442025-10-23T12:49:25Z http://pa.bibdigital.ucc.edu.ar/4944/ Diurnal ACTH and plasma cortisol variations in healthy dogs and in those with pituitary-dependent Cushing's syndrome before and after treatment with retinoic acid Castillo, V.A. Cabrera Blatter, M.F. Gómez, N.V. Sinatra, V. Gallelli, M.F. Ghersevich, María Carolina SF Cultura de los animales Daytime variations in ACTH and plasma cortisol were studied in healthy dogs and in dogs with pituitary-dependent hypercortisolism (PDH), before and after treatment with retinoic acid. In control dogs ACTH showed a higher concentration at 8.00 AM and between 2.00 and 6.00 PM, with the lowest concentration registered at 10.00 AM (p < 0.05 vs. 8.00 AM and 2.00 PM and p < 0.01 vs. 4.00 PM). Cortisol did not show significant differences. In dogs with PDH, ACTH was lower at 8.00 AM (ACTH: p < 0.01 vs. 2.00 and 4.00 PM; and p < 0.05 vs. 6.00 PM). The lowest cortisol concentration was registered at 8.00 AM and 8.00 PM and the highest at 4.00 PM (p < 0.05 vs. 8.00 AM and p < 0.01 vs. 8.00 PM). After treatment, the lowest ACTH concentration was registered at 10.00 AM (p < 0.01 vs. 2.00 and 4.00 PM). To conclude, the adrenal is desensitized in PDH possibly showing negative in diagnostic tests. 2009-12-31 info:eu-repo/semantics/article info:eu-repo/semantics/closedAccess application/pdf spa http://pa.bibdigital.ucc.edu.ar/4944/1/A_Castillo.pdf Castillo, V.A., Cabrera Blatter, M.F., Gómez, N.V., Sinatra, V., Gallelli, M.F. and Ghersevich, María Carolina ORCID: https://orcid.org/0009-0008-7577-4402 <https://orcid.org/0009-0008-7577-4402> (2009) Diurnal ACTH and plasma cortisol variations in healthy dogs and in those with pituitary-dependent Cushing's syndrome before and after treatment with retinoic acid. Research in Veterinary Science, 86 (2). pp. 223-229. ISSN 18692856 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.rvsc.2008.06.006
institution Universidad Católica de Córdoba
institution_str I-38
repository_str R-144
collection Producción Académica Universidad Católica de Córdoba (UCCor)
language Español
orig_language_str_mv spa
topic SF Cultura de los animales
spellingShingle SF Cultura de los animales
Castillo, V.A.
Cabrera Blatter, M.F.
Gómez, N.V.
Sinatra, V.
Gallelli, M.F.
Ghersevich, María Carolina
Diurnal ACTH and plasma cortisol variations in healthy dogs and in those with pituitary-dependent Cushing's syndrome before and after treatment with retinoic acid
topic_facet SF Cultura de los animales
description Daytime variations in ACTH and plasma cortisol were studied in healthy dogs and in dogs with pituitary-dependent hypercortisolism (PDH), before and after treatment with retinoic acid. In control dogs ACTH showed a higher concentration at 8.00 AM and between 2.00 and 6.00 PM, with the lowest concentration registered at 10.00 AM (p < 0.05 vs. 8.00 AM and 2.00 PM and p < 0.01 vs. 4.00 PM). Cortisol did not show significant differences. In dogs with PDH, ACTH was lower at 8.00 AM (ACTH: p < 0.01 vs. 2.00 and 4.00 PM; and p < 0.05 vs. 6.00 PM). The lowest cortisol concentration was registered at 8.00 AM and 8.00 PM and the highest at 4.00 PM (p < 0.05 vs. 8.00 AM and p < 0.01 vs. 8.00 PM). After treatment, the lowest ACTH concentration was registered at 10.00 AM (p < 0.01 vs. 2.00 and 4.00 PM). To conclude, the adrenal is desensitized in PDH possibly showing negative in diagnostic tests.
format Artículo
author Castillo, V.A.
Cabrera Blatter, M.F.
Gómez, N.V.
Sinatra, V.
Gallelli, M.F.
Ghersevich, María Carolina
author_facet Castillo, V.A.
Cabrera Blatter, M.F.
Gómez, N.V.
Sinatra, V.
Gallelli, M.F.
Ghersevich, María Carolina
author_sort Castillo, V.A.
title Diurnal ACTH and plasma cortisol variations in healthy dogs and in those with pituitary-dependent Cushing's syndrome before and after treatment with retinoic acid
title_short Diurnal ACTH and plasma cortisol variations in healthy dogs and in those with pituitary-dependent Cushing's syndrome before and after treatment with retinoic acid
title_full Diurnal ACTH and plasma cortisol variations in healthy dogs and in those with pituitary-dependent Cushing's syndrome before and after treatment with retinoic acid
title_fullStr Diurnal ACTH and plasma cortisol variations in healthy dogs and in those with pituitary-dependent Cushing's syndrome before and after treatment with retinoic acid
title_full_unstemmed Diurnal ACTH and plasma cortisol variations in healthy dogs and in those with pituitary-dependent Cushing's syndrome before and after treatment with retinoic acid
title_sort diurnal acth and plasma cortisol variations in healthy dogs and in those with pituitary-dependent cushing's syndrome before and after treatment with retinoic acid
publishDate 2009
url http://pa.bibdigital.ucc.edu.ar/4944/1/A_Castillo.pdf
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