NSAID-induced nephrotoxicity: A case report
The use of human NSAID, such as ibuprofen, poses a critical risk in veterinary medicine due to their nephrotoxicity, frequently exacerbated by self-medication by pet owners. These drugs inhibit prostaglandins that regulate renal blood flow, causing severe damage, particularly at high doses or in deh...
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| Autores principales: | , , , |
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| Formato: | Artículo revista |
| Lenguaje: | Español |
| Publicado: |
Universidad Nacional del Nordeste
2026
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| Materias: | |
| Acceso en línea: | https://revistas.unne.edu.ar/index.php/vet/article/view/9153 |
| Aporte de: |
| Sumario: | The use of human NSAID, such as ibuprofen, poses a critical risk in veterinary medicine due to their nephrotoxicity, frequently exacerbated by self-medication by pet owners. These drugs inhibit prostaglandins that regulate renal blood flow, causing severe damage, particularly at high doses or in dehydrated animals. This report presents the case of a 13-year-old male Golden Retriever that developed acute kidney injury (AKI) following ibuprofen administration, highlighting the importance of early diagnosis and appropriate clinical management. Treatment included fluid therapy and pharmacological agents aimed to alleviate clinical signs and restore renal function. It was concluded that, although the patient showed clinical improvement, NSAID-induced acute kidney injury in veterinary medicine requires continuous monitoring using specific biomarkers, which allows for early detection assessment of renal damage. |
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