Sample preparation for sequencing hits from one-bead-one-peptide combinatorial libraries by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Optimization of bead analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) after the screening of one-bead-one-peptide combinatorial libraries was achieved, involving the fine-tuning of the whole process. Guanidine was replaced by acetonitrile (MeCN)...

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Detalles Bibliográficos
Autores principales:	Giudicessi, Silvana Laura, Erra Balsells, Rosa
Publicado:	2010
Materias:	acetic acid guanidine tetrahydrofuran trifluoroacetic acid urea ambient air article crystallization elution ionization matrix assisted laser desorption ionization time of flight mass spectrometry peptide analysis priority journal process optimization sensitivity analysis tandem mass spectrometry Acetic Acid Acetonitriles Hydroxides Peptide Library Peptides Sequence Analysis, Protein Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Water
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00032697_v400_n2_p295_MartinezCeron http://hdl.handle.net/20.500.12110/paper_00032697_v400_n2_p295_MartinezCeron
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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