A 15β-hydroxywithanolide from Datura ferox
The leaves of Datura ferox yielded a new withanolide, 5α,12α,15β-trihydroxy-6α,7α-epoxy-1-oxo-22R-witha-2,24-dienolide (15β-hydroxynicandrin B), in addition to nicandrin B, withanicandrin, withastramonolide and withametelin E previously reported from Datura species. The structure and stereochemistry...
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| Autores principales: | , , |
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| Publicado: |
1995
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00319422_v40_n2_p611_Cirigliano http://hdl.handle.net/20.500.12110/paper_00319422_v40_n2_p611_Cirigliano |
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| Sumario: | The leaves of Datura ferox yielded a new withanolide, 5α,12α,15β-trihydroxy-6α,7α-epoxy-1-oxo-22R-witha-2,24-dienolide (15β-hydroxynicandrin B), in addition to nicandrin B, withanicandrin, withastramonolide and withametelin E previously reported from Datura species. The structure and stereochemistry of 15β-hydroxynicandrin B was established on the basis of spectroscopic evidence and molecular modelling. © 1995. |
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