Glucocorticoid type II receptors of the spinal cord show lower affinity than hippocampal type II receptors: Binding parameters obtained with different experimental protocols

We have used three experimental protocols to determine binding parameters for type I and type II glucocorticoid receptors in the spinal cord and hippocampus (HIPPO) from adrenalectomized rats. In protocol A, 0.5-20 nM [3H]dexamethasone (DEX) was incubated plus or minus a 1000-fold excess of unlabele...

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Guardado en:
Detalles Bibliográficos
Publicado: 1991
Materias:
dexamethasone
glucocorticoid receptor
11beta,17beta dihydroxy 6 methyl 17alpha (1 propynyl)androsta 1,4,6 trien 3 one
animal
article
binding competition
comparative study
hippocampus
male
metabolism
rat
rat strain
spinal cord
animal experiment
animal tissue
drug receptor binding
nonhuman
priority journal
Animal
Binding, Competitive
Comparative Study
Dexamethasone
Hippocampus
Male
Rats
Rats, Inbred Strains
Receptors, Glucocorticoid
Spinal Cord
Support, Non-U.S. Gov't
Support, U.S. Gov't, P.H.S.
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09600760_v39_n1_p5_Moses
http://hdl.handle.net/20.500.12110/paper_09600760_v39_n1_p5_Moses
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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