Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase
We have investigated the effect of a series of 1-amino-1,1-bisphosphonates derived from fatty acids against proliferation of the clinically more relevant form of Trypanosoma cruzi, the causative agent of American trypanosomiasis (Chagas' disease). Some of these drugs were potent inhibitors agai...
Guardado en:
| Autores principales: | Szajnman, Sergio Hernán, Ravaschino, Esteban Luis, Rodríguez, Juan Bautista |
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| Publicado: |
2005
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| Materias: | |
| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0960894X_v15_n21_p4685_Szajnman http://hdl.handle.net/20.500.12110/paper_0960894X_v15_n21_p4685_Szajnman |
| Aporte de: |
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