A New Depigmenting-Antifungal Methylated Grindelane from Grindelia chiloensis

The new methylated grindelane diterpenoid, 7β-hydroxy-8(17)-dehydrogrindelic acid (1b), together with the known 7α-hydroxy-8(17)-dehydrogrindelic acid (2a), 6-oxogrindelic acid (3a), 4β-hydroxy-6-oxo-19-norgrindelic (4a), 19-hydroxygrindelic acid (5a), 18-hydroxygrindelic acid (6a), 4α-carboxygrinde...

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Detalles Bibliográficos
Publicado:	2017
Materias:	Antifungal and depigmenting effects Botrytis cinerea Fusarium oxysporum Grindelane diterpenoids and derivatives Grindelia chiloensis 6 oxogrindelic acid 7alpha,8alpha epoxygrindelic acid antifungal agent azoxystrobin depigmenting agent diterpenoid enilconazole ester derivative methyl 17 hydroxygrindelate methyl 17alpha hydroxy 8(17) dehydrogrindelate methyl 18 hydroxygrindelate methyl 19 hydroxygrindelate methyl 4 beta hydroxy 6 oxo 19 norgrindelate methyl 4alpha carbomethoxigrindelate methyl 6alpha ydroxygrindelate methyl 7beta hydroxy 8(17) dehydrogrindelate methyl 8,17 bisnor 8 oxagrindelate methyl strictanoate unclassified drug diterpene ent-7beta,11alpha,14-trihydroxy-18-aldehyde-11beta-20-epoxy-kaur-16-en15-one plant extract antifungal activity Argentina Article carbon nuclear magnetic resonance controlled study dose response Grindelia growth inhibition heteronuclear multiple bond correlation heteronuclear multiple quantum coherence IC50 methylation mycelial growth nonhuman pigmentation proton nuclear magnetic resonance ultraviolet radiation chemical structure chemistry drug effects Fusarium isolation and purification nuclear magnetic resonance spectroscopy Antifungal Agents Diterpenes Magnetic Resonance Spectroscopy Molecular Structure Plant Extracts Skin Lightening Preparations
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_16121872_v14_n5_p_delosAMesurado http://hdl.handle.net/20.500.12110/paper_16121872_v14_n5_p_delosAMesurado
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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