Synthesis of α-D-galactofuranosyl phosphate

D-Galactofuranosyl units (Galf), mainly in the β-configuration, are constituents of infectious microorganisms, such as the Mycobacteria, trypanosomatids like Trypanosoma cruzi and Leishmania, and fungi like Aspergillus fumigatus. Several chemical syntheses of the Galf nucleotide have been reported....

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Publicado: 2014
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97814398_v2_n_p223_Marino
http://hdl.handle.net/20.500.12110/paper_97814398_v2_n_p223_Marino
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spelling paper:paper_97814398_v2_n_p223_Marino2023-06-08T16:37:26Z Synthesis of α-D-galactofuranosyl phosphate D-Galactofuranosyl units (Galf), mainly in the β-configuration, are constituents of infectious microorganisms, such as the Mycobacteria, trypanosomatids like Trypanosoma cruzi and Leishmania, and fungi like Aspergillus fumigatus. Several chemical syntheses of the Galf nucleotide have been reported. Recently, an effective chemoenzymatic procedure for the preparation of UDP-Galf was described in detail. The chemical and enzymatic methods start with α-D-Galf phosphate, prepared for the first time by Lederkremer et al. Starting from α-D-[6-3H]-Galf phosphate, the radioactive nucleotide, useful for metabolic studies, was chemically synthesized. © 2014 by Taylor & Francis Group, LLC. 2014 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97814398_v2_n_p223_Marino http://hdl.handle.net/20.500.12110/paper_97814398_v2_n_p223_Marino
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
description D-Galactofuranosyl units (Galf), mainly in the β-configuration, are constituents of infectious microorganisms, such as the Mycobacteria, trypanosomatids like Trypanosoma cruzi and Leishmania, and fungi like Aspergillus fumigatus. Several chemical syntheses of the Galf nucleotide have been reported. Recently, an effective chemoenzymatic procedure for the preparation of UDP-Galf was described in detail. The chemical and enzymatic methods start with α-D-Galf phosphate, prepared for the first time by Lederkremer et al. Starting from α-D-[6-3H]-Galf phosphate, the radioactive nucleotide, useful for metabolic studies, was chemically synthesized. © 2014 by Taylor & Francis Group, LLC.
title Synthesis of α-D-galactofuranosyl phosphate
spellingShingle Synthesis of α-D-galactofuranosyl phosphate
title_short Synthesis of α-D-galactofuranosyl phosphate
title_full Synthesis of α-D-galactofuranosyl phosphate
title_fullStr Synthesis of α-D-galactofuranosyl phosphate
title_full_unstemmed Synthesis of α-D-galactofuranosyl phosphate
title_sort synthesis of α-d-galactofuranosyl phosphate
publishDate 2014
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_97814398_v2_n_p223_Marino
http://hdl.handle.net/20.500.12110/paper_97814398_v2_n_p223_Marino
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