A novel mechanism of resistance to α-difluoromethylornithine induced by cycloheximide. Growth with abnormally low levels of putrescine and spermidine
Treatment of the chemically transformed fibroblasts BP-A31 and other cell lines with low concentrations of cycloheximide (CHM) for 72 h followed by the removal of the protein synthesis inhibitor leads to the proliferation of α-difluoromethylornithine (DFMO)-resistant phenotypes. These drug-resistant...
Guardado en:
| Autores principales: | Medrano, E.E., Burrone, O.R., Ferrer, M.M., Cafferata, E.G.A., Algranati, I.D. |
|---|---|
| Formato: | Artículo publishedVersion |
| Lenguaje: | Inglés |
| Publicado: |
1986
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00145793_v206_n1_p106_Medrano |
| Aporte de: |
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