Effects of chlorate on the sulfation process of trypanosoma cruzi glycoconjugates. Implication of parasite sulfates in cellular invasion

Sulfation, a post-translational modification which plays a key role in various biological processes, is inhibited by competition with chlorate. In Trypanosoma cruzi, the agent of Chagas' disease, sulfated structures have been described as part of glycolipids and we have reported sulfated high-m...

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Detalles Bibliográficos
Autores principales:	Ferrero, M.R., Soprano, L.L., Acosta, D.M., García, G.A., Esteva, M.I., Couto, A.S., Duschak, V.G.
Formato:	JOUR
Materias:	Cruzipain Invasion process Sulfation Sulfoglycosphingolipids Trypanosoma cruzi chlorate cruzipain cruzipain antibody enzyme antibody glycoconjugate immunoglobulin G mannose receptor mannose receptor antibody receptor antibody sulfatide unclassified drug cysteine proteinase sulfate antibody electron microscopy lipid membrane metabolism parasite amastigote animal cell antibody specificity article cell invasion cell organelle cell ultrastructure controlled study epimastigote flow cytometry gel mobility shift assay host parasite interaction immunoblotting isoelectric point lipid reservosome matrix assisted laser desorption ionization time of flight mass spectrometry nonhuman polyacrylamide gel electrophoresis sulfation thin layer chromatography trypomastigote ultraviolet spectroscopy animal cell line drug effects endocytosis heart muscle cell human mass spectrometry parasitology physiology protein processing rabbit two dimensional gel electrophoresis Animals Cell Line Chlorates Cysteine Endopeptidases Electrophoresis, Gel, Two-Dimensional Endocytosis Glycoconjugates Humans Immunoblotting Isoelectric Point Metabolic Networks and Pathways Microscopy, Electron Myocytes, Cardiac Protein Processing, Post-Translational Rabbits Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Sulfates
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_0001706X_v137_n_p161_Ferrero
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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