Evaluation of in-house ELISA using Trypanosoma cruzi lysate and recombinant antigens for diagnosis of chagas disease and discrimination of its clinical forms

The aim of this work was to investigate the potential usefulness of Trypanosoma cruzi lysate, recombinant protein JL7, and peptides P013, R13, JL18, JL19, and P0b as serological markers for human Chagas disease. We analyzed 228 sera from Brazilian Chagas disease patients classified into four clinica...

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Detalles Bibliográficos
Autores principales: Longhi, S.A., Brandariz, S.B., Lafon, S.O., Niborski, L.L., Luquetti, A.O., Schijman, A.G., Levin, M.J., Gómez, K.A.
Formato: JOUR
Materias:
bacterium lysate
peptide
peptide jl18
peptide jl19
peptide p013
peptide p0beta
peptide r13
recombinant antigen
recombinant protein
recombinant protein jl7
unclassified drug
adolescent
adult
article
blood sampling
Brazil
Chagas disease
child
controlled study
cross reaction
disease severity
enzyme linked immunosorbent assay
female
human
immunofluorescence
major clinical study
male
school child
sensitivity and specificity
serology
Trypanosoma cruzi
visceral leishmaniasis
Adolescent
Adult
Animals
Antibodies, Protozoan
Antigens, Protozoan
Chagas Disease
Child
Enzyme-Linked Immunosorbent Assay
Female
Humans
Male
Middle Aged
Recombinant Proteins
Sensitivity and Specificity
Young Adult
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00029637_v87_n2_p267_Longhi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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