1-Cinnamoyl-3,11-dihydroxymeliacarpin is a natural bioactive compound with antiviral and nuclear factor-κB modulating properties

We have reported the isolation of the tetranortriterpenoid 1-cinnamoyl-3,11-dihydroxymeliacarpin (CDM) from partially purified leaf extracts of Melia azedarach L. (MA) that reduced both, vesicular stomatitis virus (VSV) and Herpes simplex virus type 1 (HSV-1) multiplication. CDM blocks VSV entry and...

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Detalles Bibliográficos
Autores principales:	Barquero, A.A., Michelini, F.M., Alché, L.E.
Formato:	JOUR
Materias:	1-Cinnamoyl-3,11-dihydroxymeliacarpin Antiinflammatory Herpes simplex virus type 1 Melia azedarach L. Natural antiviral NF-κB Triterpenoids 1 cinnamoyl 3,11 dihydroxymeliacarpin antivirus agent terpenoid derivative unclassified drug 1-cinnamoyl-3,11-dihydroxymeliacarpin immunoglobulin enhancer binding protein limonoid animal cell article controlled study DNA replication DNA virus Golgi complex Herpes simplex virus host cell immunomodulation membrane transport nonhuman priority journal purification RNA replication RNA virus Vesicular stomatitis virus virogenesis animal cell line Cercopithecus conjunctiva dose response drug effect growth, development and aging Herpes simplex virus 1 human metabolism physiology Vero cell virology virus replication Human herpesvirus 1 Melia azedarach RNA viruses Animals Antiviral Agents Cell Line Cercopithecus aethiops Conjunctiva Dose-Response Relationship, Drug Herpesvirus 1, Human Humans Limonins NF-kappa B Vero Cells Virus Replication
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_0006291X_v344_n3_p955_Barquero
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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