Estimation of ion channel kinetics from fluctuations of macroscopic currents
For single channel recordings, the maximum likelihood estimation (MLE) of kinetic rates and conductance is well established. A direct extrapolation of this method to macroscopic currents is computationally prohibitive: it scales as a power of the number of channels. An approximated MLE that ignored...
| Autor principal: | Moffatt, L. |
|---|---|
| Formato: | JOUR |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00063495_v93_n1_p74_Moffatt |
| Aporte de: |
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