Tissue distribution and kinetics of endogenous porphyrins synthesized after topical application of ALA in different vehicles

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The use of 5-aminolaevulinic acid (ALA) is gaining increasing attention for photosensitization in photodynamic therapy of superficially localized tumours. The aim of this work was to determine the kinetics of porphyrin generation in tissues after topical application of ALA delivered in different veh...

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Detalles Bibliográficos
Autores principales: Casas, A., Fukuda, H., Del C Batlle, A.M.
Formato: JOUR
Materias:
5-Aminolaevulinic acid
ALA cream
ALA lotion
ALA-PDT
Topical application
aminolevulinic acid
drug vehicle
photosensitizing agent
porphyrin
animal experiment
animal model
animal tissue
article
cancer therapy
controlled study
cream
feces level
kidney
kinetics
liver
lotion
male
mouse
nonhuman
photodynamic therapy
priority journal
skin
spleen
tissue distribution
topical drug administration
urine level
Adenocarcinoma
Administration, Topical
Aminolevulinic Acid
Animals
Kinetics
Male
Mammary Neoplasms, Experimental
Mice
Mice, Inbred BALB C
Neoplasm Transplantation
Photosensitizing Agents
Porphyrins
Tissue Distribution
Vehicles
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00070920_v81_n1_p13_Casas
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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