Inclusion complex of 2-chlorobenzophenone with cyclomaltoheptaose (β-cyclodextrin): Temperature, solvent effects and molecular modeling

A thermodynamic study of the inclusion process between 2-chlorobenzophenone (2ClBP) and cyclomaltoheptaose (β-cyclodextrin, β-CD) was performed using UV-vis spectroscopy, reversed-phase liquid chromatography (RP-HPLC), and molecular modeling (PM6). Spectrophotometric measurements in aqueous solution...

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Detalles Bibliográficos
Autores principales:	Sancho, M.I., Gasull, E., Blanco, S.E., Castro, E.A.
Formato:	JOUR
Materias:	2-Chlorobenzophenone Apparent formation constants Molecular modeling Reversed-phase liquid chromatography Solubility β-Cyclodextrin Chromatography Cyclodextrins Enthalpy Solutions Solvents Temperature Temperature distribution Ultraviolet visible spectroscopy Formation constants Mobile-phase composition Reversed phase liquid-chromatography Semi-empirical methods Spectrophotometric measurements Temperature dependence Thermodynamic parameter Liquid chromatography 2 chlorobenzophenone benzophenone derivative beta cyclodextrin unclassified drug article controlled study drug solubility encapsulation enthalpy entropy molecular model priority journal reversed phase high performance liquid chromatography solvent effect stoichiometry temperature thermodynamics ultraviolet spectroscopy
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00086215_v346_n13_p1978_Sancho
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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