A role for the endogenous opioid β-endorphin in energy homeostasis

Proopiomelanocortin (POMC) neurons in the hypothalamus are direct targets of the adipostatic hormone leptin and contribute to energy homeostasis by integrating peripheral and central information. The melanocortin and β-endorphin neuropeptides are processed from POMC and putatively coreleased at axon...

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Detalles Bibliográficos
Autores principales: Appleyard, S.M., Hayward, M., Young, J.I., Butler, A.A., Cone, R.D., Rubinstein, M., Low, M.J.
Formato: JOUR
Materias:
beta endorphin
leptin
melanocortin
naloxone
neuropeptide
opiate
opiate antagonist
proopiomelanocortin
glucose
narcotic antagonist
neuropeptide Y
animal experiment
animal model
animal tissue
anorexia
article
body weight
controlled study
energy balance
food intake
hyperphagia
hypothalamus
male
mouse
nerve ending
nonhuman
obesity
priority journal
animal
blood
drug effect
eating
energy metabolism
homeostasis
hyperinsulinism
metabolism
mouse mutant
physiology
reference value
Animals
beta-Endorphin
Eating
Energy Metabolism
Glucose
Homeostasis
Hyperinsulinism
Hyperphagia
Leptin
Male
Mice
Mice, Knockout
Naloxone
Narcotic Antagonists
Neuropeptide Y
Obesity
Reference Values
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00137227_v144_n5_p1753_Appleyard
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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